S Illinois
Southern Illinois Salukis · Carbondale, IL
Missouri Valley Football Conference · FCS
All teams · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 8/30 | A | E Illinois (7-4) | [FCS:OVC] | L | 28-49 | |
| 9/8 | A | Miami OH (4-8) | [G5:MAC] | L | 14-30 | |
| 9/15 | H | SE Missouri (3-8) | [FCS:OVC] | W | 35-14 | |
| 9/22 | A | Missouri St (3-8) | [FCS:MVFC] | W | 14-6 | |
| 9/29 | H | Indiana St (7-4) | [FCS:MVFC] | L | 3-24 | |
| 10/6 | A | Illinois St (8-3) | [FCS:MVFC] | W | 17-0 | |
| 10/13 | H | Northern Iowa (5-6) | [FCS:MVFC] | W | 34-31 | |
| 10/20 | A | Youngstown St (7-4) | [FCS:MVFC] | W | 38-21 | |
| 10/27 | A | N Dakota St (10-1) | [FCS:MVFC] | L | 17-23 | |
| 11/3 | H | S Dakota St (8-3) | [FCS:MVFC] | L | 12-16 | |
| 11/17 | H | W Illinois (3-8) | [FCS:MVFC] | W | 35-0 |