S Illinois
Southern Illinois Salukis · Carbondale, IL
Missouri Valley Football Conference · FCS
All teams · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 8/28 | H | Taylor | [Lower] | W | 45-0 | |
| 9/6 | A | E Illinois (5-7) | [FCS:OVC] | W | 38-21 | |
| 9/13 | H | SE Missouri (5-7) | [FCS:OVC] | W | 50-23 | |
| 9/20 | A | Purdue (3-9) | [P4:Big Ten] | L | 13-35 | |
| 9/27 | H | W Illinois (5-7) | [FCS:MVFC] | W | 34-17 | |
| 10/4 | H | South Dakota (2-10) | [FCS:MVFC] | W | 41-10 | |
| 10/11 | A | N Dakota St (11-1) | [FCS:MVFC] | L | 10-38 | |
| 10/18 | A | Youngstown St (7-5) | [FCS:MVFC] | L | 14-26 | |
| 10/25 | H | Indiana St (7-5) | [FCS:MVFC] | L | 26-41 | |
| 11/8 | A | Missouri St (4-8) | [FCS:MVFC] | W | 32-22 | |
| 11/15 | H | Northern Iowa (8-4) | [FCS:MVFC] | L | 21-40 | |
| 11/22 | A | Illinois St (10-1) | [FCS:MVFC] | L | 29-44 |