S Illinois
Southern Illinois Salukis · Carbondale, IL
Missouri Valley Football Conference · FCS
All teams · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 8/31 | A | Illinois (4-8) | [P4:Big Ten] | L | 34-42 | |
| 9/7 | H | E Illinois (11-1) | [FCS:OVC] | L | 37-40 | |
| 9/14 | H | Charleston (WV) | [Lower] | W | 31-10 | |
| 9/21 | N | SE Missouri (3-9) | [FCS:OVC] | W | 36-19 | AT ST. LOUIS |
| 9/28 | H | Youngstown St (8-4) | [FCS:MVFC] | L | 27-28 | |
| 10/5 | A | S Dakota St (8-4) | [FCS:MVFC] | W | 27-24 | |
| 10/12 | A | Northern Iowa (7-5) | [FCS:MVFC] | W | 24-17 | |
| 10/19 | H | N Dakota St (11-0) | [FCS:MVFC] | L | 10-31 | |
| 11/2 | A | W Illinois (4-8) | [FCS:MVFC] | W | 34-28 | |
| 11/9 | H | Missouri St (5-7) | [FCS:MVFC] | L | 27-37 | |
| 11/16 | H | Illinois St (5-6) | [FCS:MVFC] | W | 24-17 | |
| 11/23 | A | Indiana St (1-11) | [FCS:MVFC] | W | 31-9 |