S Illinois
Southern Illinois Salukis · Carbondale, IL
Missouri Valley Football Conference · FCS
All teams · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 8/29 | A | SE Missouri (9-3) | [FCS:OVC] | L | 26-44 | |
| 9/7 | A | UMass (1-11) | [G5:Ind] | W | 45-20 | |
| 9/14 | H | UT Martin (7-5) | [FCS:OVC] | W | 28-14 | |
| 9/21 | A | Arkansas St (7-5) | [G5:Sun Belt] | L | 28-41 | |
| 10/5 | A | S Dakota St (8-4) | [FCS:MVFC] | L | 10-28 | |
| 10/12 | H | Illinois St (8-4) | [FCS:MVFC] | L | 7-21 | |
| 10/19 | H | Youngstown St (6-6) | [FCS:MVFC] | W | 35-10 | |
| 10/26 | A | South Dakota (5-7) | [FCS:MVFC] | W | 48-28 | |
| 11/2 | A | Indiana St (5-7) | [FCS:MVFC] | W | 23-14 | |
| 11/9 | H | Missouri St (1-10) | [FCS:MVFC] | W | 37-14 | |
| 11/16 | A | W Illinois (1-11) | [FCS:MVFC] | W | 45-21 | |
| 11/23 | H | N Dakota St (12-0) | [FCS:MVFC] | L | 7-21 |