S Illinois
Southern Illinois Salukis · Carbondale, IL
Missouri Valley Football Conference · FCS
All teams · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/3 | A | SE Missouri (3-8) | [FCS:OVC] | W | 38-10 | |
| 9/10 | A | Ole Miss (2-10) | [P4:SEC] | L | 24-42 | |
| 9/24 | H | Missouri St (2-9) | [FCS:MVFC] | W | 20-18 | |
| 10/1 | A | W Illinois (2-9) | [FCS:MVFC] | L | 21-27 | |
| 10/8 | H | N Dakota St (10-1) | [FCS:MVFC] | L | 3-9 | |
| 10/15 | H | Youngstown St (6-5) | [FCS:MVFC] | L | 23-35 | |
| 10/22 | A | Northern Iowa (9-2) | [FCS:MVFC] | L | 10-17 | |
| 10/29 | H | Illinois St (7-4) | [FCS:MVFC] | L | 30-38 | |
| 11/5 | A | S Dakota St (5-6) | [FCS:MVFC] | L | 34-45 | |
| 11/12 | H | E Illinois (2-9) | [FCS:OVC] | W | 45-28 | |
| 11/19 | A | Indiana St (6-5) | [FCS:MVFC] | W | 35-28 |