Big 12 rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/4 | H | Tulsa (4-8) | [G5:WAC] | W | 21-3 | |
| 9/11 | H | Toledo (9-3) | [G5:MAC] | W | 63-14 | |
| 9/18 | A | Northwestern (6-6) | [P4:Big Ten] | L | 17-20 | |
| 9/25 | H | Texas Tech (7-4) | [P4:Big 12] | L | 30-31 | |
| 10/2 | A | Nebraska (5-6) | [P4:Big 12] | L | 8-14 | |
| 10/9 | H | Kansas St (4-7) | [P4:Big 12] | W | 31-28 | |
| 10/23 | A | Oklahoma (12-0) | [P4:Big 12] | L | 10-41 | |
| 10/30 | A | Iowa State (6-5) | [P4:Big 12] | L | 7-13 | |
| 11/6 | H | Colorado (7-5) | [P4:Big 12] | L | 21-30 | |
| 11/13 | H | Texas (10-1) | [P4:Big 12] | L | 23-27 | |
| 11/20 | A | Missouri (5-6) | [P4:Big 12] | W | 31-14 |