Big 12 rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/2 | H | N'Western St (4-7) | [FCS:LAND] | W | 49-18 | |
| 9/9 | H | UL Monroe (4-8) | [G5:Sun Belt] | W | 21-19 | |
| 9/15 | A | Toledo (5-7) | [G5:MAC] | L | 31-37 | |
| 9/23 | H | South Florida (8-4) | [P4:Big East] | W | 13-7 | |
| 9/30 | A | Nebraska (9-4) | [P4:Big 12] | L | 32-39 | |
| 10/7 | H | Texas A&M (9-3) | [P4:Big 12] | L | 18-21 | |
| 10/14 | H | Oklahoma St (6-6) | [P4:Big 12] | L | 32-42 | |
| 10/21 | A | Baylor (4-8) | [P4:Big 12] | L | 35-36 | |
| 10/28 | H | Colorado (2-10) | [P4:Big 12] | W | 20-15 | |
| 11/4 | A | Iowa State (4-8) | [P4:Big 12] | W | 41-10 | |
| 11/18 | H | Kansas St (7-5) | [P4:Big 12] | W | 39-20 | |
| 11/25 | A | Missouri (8-4) | [P4:Big 12] | L | 17-42 |