Big 12 rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 8/23 | H | Fresno St (8-4) | [G5:MWC] | W | 31-7 | |
| 8/29 | H | Wagner (5-7) | [FCS:NEAST] | W | 46-7 | |
| 9/6 | A | Missouri (8-4) | [P4:SEC] | L | 31-42 | |
| 9/20 | H | West Virginia (4-8) | [P4:Big 12] | W | 41-10 | |
| 9/27 | H | Cincinnati (7-5) | [P4:Big 12] | L | 34-37 | |
| 10/4 | A | UCF (5-7) | [P4:Big 12] | W | 27-20 | |
| 10/11 | A | Texas Tech (12-1) | [P4:Big 12] | L | 17-42 | |
| 10/25 | H | Kansas St (6-6) | [P4:Big 12] | L | 17-42 | |
| 11/1 | H | Oklahoma St (1-11) | [P4:Big 12] | W | 38-21 | |
| 11/8 | A | Arizona (9-3) | [P4:Big 12] | L | 20-24 | |
| 11/22 | A | Iowa State (8-4) | [P4:Big 12] | L | 14-38 | |
| 11/28 | H | Utah (10-2) | [P4:Big 12] | L | 21-31 |