Big 12 rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 8/31 | H | Indiana St (5-7) | [FCS:MVFC] | W | 24-17 | |
| 9/7 | H | Coastal (5-7) | [G5:Sun Belt] | L | 7-12 | |
| 9/13 | A | Boston College (6-6) | [P4:ACC] | W | 48-24 | |
| 9/21 | H | West Virginia (5-7) | [P4:Big 12] | L | 24-29 | |
| 9/28 | A | TCU (5-7) | [P4:Big 12] | L | 14-51 | |
| 10/5 | H | Oklahoma (12-1) | [P4:Big 12] | L | 20-45 | |
| 10/19 | A | Texas (7-5) | [P4:Big 12] | L | 48-50 | |
| 10/26 | H | Texas Tech (4-8) | [P4:Big 12] | W | 37-34 | |
| 11/2 | H | Kansas St (8-4) | [P4:Big 12] | L | 10-38 | |
| 11/16 | A | Oklahoma St (8-4) | [P4:Big 12] | L | 13-31 | |
| 11/23 | A | Iowa State (7-5) | [P4:Big 12] | L | 31-41 | |
| 11/30 | H | Baylor (11-2) | [P4:Big 12] | L | 6-61 |