Big Ten rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 8/30 | A | Missouri (8-4) | [P4:Big 12] | L | 15-22 | AT ST LOUIS |
| 9/6 | H | Illinois St (6-6) | [FCS:MVFC] | W | 49-22 | |
| 9/13 | A | UCLA (6-6) | [P4:Pac-12] | L | 3-6 | |
| 9/20 | H | California (7-6) | [P4:Pac-12] | L | 24-31 | |
| 9/27 | H | Wisconsin (7-5) | [P4:Big Ten] | L | 20-38 | |
| 10/4 | A | Purdue (9-3) | [P4:Big Ten] | L | 10-43 | |
| 10/11 | H | Michigan St (8-4) | [P4:Big Ten] | L | 14-49 | |
| 10/18 | A | Michigan (10-2) | [P4:Big Ten] | L | 14-56 | |
| 10/25 | H | Minnesota (9-3) | [P4:Big Ten] | L | 10-36 | |
| 11/1 | A | Iowa (9-3) | [P4:Big Ten] | L | 10-41 | |
| 11/8 | A | Indiana (2-10) | [P4:Big Ten] | L | 14-17 | |
| 11/22 | H | Northwestern (6-6) | [P4:Big Ten] | L | 20-37 |