Big Ten rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 8/28 | H | Nebraska (3-9) | [P4:Big Ten] | W | 30-22 | |
| 9/4 | H | UTSA (12-1) | [G5:CUSA] | L | 30-37 | |
| 9/11 | A | Virginia (6-6) | [P4:ACC] | L | 14-42 | |
| 9/17 | H | Maryland (6-6) | [P4:Big Ten] | L | 17-20 | |
| 9/25 | A | Purdue (8-4) | [P4:Big Ten] | L | 9-13 | |
| 10/2 | H | Charlotte (5-7) | [G5:CUSA] | W | 24-14 | |
| 10/9 | H | Wisconsin (8-4) | [P4:Big Ten] | L | 0-24 | |
| 10/23 | A | Penn State (7-5) | [P4:Big Ten] | W | 20-18 | |
| 10/30 | H | Rutgers (5-7) | [P4:Big Ten] | L | 14-20 | |
| 11/6 | A | Minnesota (8-4) | [P4:Big Ten] | W | 14-6 | |
| 11/20 | A | Iowa (10-3) | [P4:Big Ten] | L | 23-33 | |
| 11/27 | H | Northwestern (3-9) | [P4:Big Ten] | W | 47-14 |