Big Ten rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/3 | H | UAB (4-3) | [G5:AAC] | W | 42-23 | |
| 9/12 | H | Duke (4-1) | [P4:ACC] | L | 27-31 | |
| 9/19 | H | S Illinois (3-4) | [FCS:MVFC] | W | 48-10 | |
| 9/26 | A | Ohio State (5-1) | [P4:Big Ten] | L | 19-42 | |
| 10/3 | H | Purdue (3-4) | [P4:Big Ten] | L | 17-24 | |
| 10/10 | A | Michigan St (2-4) | [P4:Big Ten] | W | 38-37 | |
| 10/24 | H | Oregon (3-2) | [P4:Big Ten] | |||
| 10/31 | A | Maryland (2-4) | [P4:Big Ten] | |||
| 11/6 | H | Nebraska (5-1) | [P4:Big Ten] | |||
| 11/13 | A | UCLA (5-0) | [P4:Big Ten] | |||
| 11/21 | H | Iowa (5-1) | [P4:Big Ten] | |||
| 11/28 | A | Northwestern (4-1) | [P4:Big Ten] |