Big Ten rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 8/31 | H | Missouri (5-7) | [P4:Big 12] | L | 20-33 | |
| 9/7 | A | Southern Miss (7-5) | [G5:CUSA] | L | 20-23 | |
| 9/14 | H | Arkansas St (6-7) | [G5:Sun Belt] | W | 59-7 | |
| 9/21 | H | San José St (6-7) | [G5:WAC] | L | 35-38 | |
| 9/28 | H | Michigan (9-3) | [P4:Big Ten] | L | 28-45 | |
| 10/3 | A | Minnesota (7-5) | [P4:Big Ten] | L | 10-31 | |
| 10/12 | H | Purdue (6-6) | [P4:Big Ten] | W | 38-31 | |
| 10/26 | H | Indiana (3-9) | [P4:Big Ten] | W | 45-14 | |
| 11/2 | A | Penn State (9-3) | [P4:Big Ten] | L | 7-18 | |
| 11/9 | A | Wisconsin (7-6) | [P4:Big Ten] | W | 37-20 | |
| 11/16 | H | Ohio State (13-0) | [P4:Big Ten] | L | 16-23 | |
| 11/23 | A | Northwestern (3-9) | [P4:Big Ten] | W | 31-24 |