Big Ten rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/4 | H | Florida A&M (3-8) | [FCS:MEAC] | W | 52-13 | |
| 9/11 | H | UCLA (6-5) | [P4:Pac-12] | L | 17-35 | |
| 9/18 | H | W Michigan (1-10) | [G5:MAC] | W | 30-27 | |
| 9/25 | H | Purdue (7-4) | [P4:Big Ten] | L | 30-38 | |
| 10/2 | A | Wisconsin (9-2) | [P4:Big Ten] | L | 7-24 | |
| 10/9 | A | Michigan St (5-7) | [P4:Big Ten] | L | 25-38 | |
| 10/16 | H | Michigan (9-2) | [P4:Big Ten] | L | 19-30 | |
| 10/23 | A | Minnesota (6-5) | [P4:Big Ten] | L | 0-45 | |
| 10/30 | H | Iowa (9-2) | [P4:Big Ten] | L | 13-23 | |
| 11/6 | H | Indiana (3-8) | [P4:Big Ten] | W | 26-22 | |
| 11/20 | A | Northwestern (6-6) | [P4:Big Ten] | L | 21-28 |