Big 12 rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 8/31 | A | Illinois (5-7) | [P4:Big Ten] | W | 33-20 | |
| 9/7 | H | Ball State (6-6) | [G5:MAC] | W | 41-6 | |
| 9/14 | A | Bowling Green (9-3) | [G5:MAC] | L | 28-51 | |
| 9/28 | H | Troy (4-8) | [G5:Ind] | W | 44-7 | |
| 10/5 | H | Oklahoma (11-2) | [P4:Big 12] | L | 24-31 | |
| 10/12 | A | Nebraska (7-6) | [P4:Big 12] | L | 13-24 | |
| 10/19 | A | Texas Tech (8-5) | [P4:Big 12] | L | 38-52 | |
| 10/26 | H | Kansas (2-10) | [P4:Big 12] | W | 36-12 | |
| 11/2 | A | Iowa State (7-6) | [P4:Big 12] | L | 35-42 | |
| 11/9 | H | Colorado (9-4) | [P4:Big 12] | L | 35-42 | |
| 11/16 | A | Texas A&M (6-6) | [P4:Big 12] | W | 33-27 | |
| 11/23 | H | Kansas St (10-2) | [P4:Big 12] | L | 0-38 |