Big 12 rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 8/23 | N | Kansas St (6-6) | [P4:Big 12] | W | 24-21 | Aer Lingus College Football Classic |
| 8/30 | H | South Dakota (8-4) | [FCS:MVFC] | W | 55-7 | |
| 9/6 | H | Iowa (8-4) | [P4:Big Ten] | W | 16-13 | |
| 9/13 | A | Arkansas St (6-6) | [G5:Sun Belt] | W | 24-16 | |
| 9/27 | H | Arizona (9-3) | [P4:Big 12] | W | 39-14 | |
| 10/4 | A | Cincinnati (7-5) | [P4:Big 12] | L | 30-38 | |
| 10/11 | A | Colorado (3-9) | [P4:Big 12] | L | 17-24 | |
| 10/25 | H | BYU (11-2) | [P4:Big 12] | L | 27-41 | |
| 11/1 | H | Arizona St (8-4) | [P4:Big 12] | L | 19-24 | |
| 11/8 | A | TCU (8-4) | [P4:Big 12] | W | 20-17 | |
| 11/22 | H | Kansas (5-7) | [P4:Big 12] | W | 38-14 | |
| 11/29 | A | Oklahoma St (1-11) | [P4:Big 12] | W | 20-13 |