Big 12 rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/2 | H | Montana St (7-4) | [FCS:BSKY] | L | 10-19 | |
| 9/9 | A | Colorado St (4-8) | [G5:MWC] | L | 10-14 | AT DENVER CO |
| 9/16 | H | Arizona St (7-5) | [P4:Pac-12] | L | 3-21 | |
| 9/23 | A | Georgia (8-4) | [P4:SEC] | L | 13-14 | |
| 9/30 | A | Missouri (8-4) | [P4:Big 12] | L | 13-28 | |
| 10/7 | H | Baylor (4-8) | [P4:Big 12] | L | 31-34 | |
| 10/14 | H | Texas Tech (7-5) | [P4:Big 12] | W | 30-6 | |
| 10/21 | A | Oklahoma (11-2) | [P4:Big 12] | L | 3-24 | |
| 10/28 | A | Kansas (6-6) | [P4:Big 12] | L | 15-20 | |
| 11/4 | H | Kansas St (7-5) | [P4:Big 12] | L | 21-34 | |
| 11/11 | H | Iowa State (4-8) | [P4:Big 12] | W | 33-16 | |
| 11/24 | A | Nebraska (9-4) | [P4:Big 12] | L | 14-37 |