Big East rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/1 | H | Wake Forest (6-6) | [P4:ACC] | W | 36-29 | |
| 9/10 | H | Rhode Island (3-8) | [FCS:CAA] | W | 21-14 | |
| 9/17 | A | USC (10-2) | [P4:Pac-12] | L | 17-38 | |
| 9/24 | H | Toledo (8-4) | [G5:MAC] | W | 33-30 | |
| 10/1 | H | Rutgers (8-4) | [P4:Big East] | L | 16-19 | |
| 10/8 | A | Tulane (2-11) | [G5:CUSA] | W | 37-34 | |
| 10/21 | H | West Virginia (9-3) | [P4:Big East] | W | 49-23 | |
| 10/29 | A | Louisville (7-5) | [P4:Big East] | L | 10-27 | |
| 11/5 | A | UConn (5-7) | [P4:Big East] | L | 21-28 | |
| 11/11 | H | South Florida (5-7) | [P4:Big East] | L | 17-37 | |
| 11/26 | H | Cincinnati (9-3) | [P4:Big East] | L | 13-30 | |
| 12/3 | A | Pitt (6-6) | [P4:Big East] | L | 20-33 |