Big East rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 8/30 | A | Northwestern (9-3) | [P4:Big Ten] | L | 10-30 | |
| 9/6 | H | Akron (5-7) | [G5:MAC] | L | 28-42 | |
| 9/13 | H | Penn State (11-1) | [P4:Big Ten] | L | 13-55 | |
| 9/20 | H | Northeastern (2-10) | [FCS:CAA] | W | 30-21 | |
| 9/27 | H | Pitt (9-3) | [P4:Big East] | L | 24-34 | |
| 10/11 | A | West Virginia (8-4) | [P4:Big East] | L | 6-17 | |
| 10/18 | A | South Florida (7-5) | [P4:Big East] | L | 13-45 | |
| 11/1 | H | Louisville (5-7) | [P4:Big East] | W | 28-21 | |
| 11/8 | A | Rutgers (7-5) | [P4:Big East] | L | 17-35 | |
| 11/15 | H | UConn (7-5) | [P4:Big East] | L | 14-39 | |
| 11/22 | A | Notre Dame (6-6) | [P4:Ind] | W | 24-23 | |
| 11/29 | A | Cincinnati (11-2) | [P4:Big East] | L | 10-30 |