Big East rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/1 | H | Fordham (1-10) | [FCS:PAT] | postponed | ||
| 9/3 | H | Fordham (1-10) | [FCS:PAT] | W | 35-3 | |
| 9/10 | A | Vanderbilt (6-6) | [P4:SEC] | L | 21-24 | |
| 9/16 | H | Iowa State (6-6) | [P4:Big 12] | L | 20-24 | |
| 9/24 | A | Buffalo (3-9) | [G5:MAC] | W | 17-3 | |
| 10/1 | H | W Michigan (7-5) | [G5:MAC] | L | 31-38 | |
| 10/8 | A | West Virginia (9-3) | [P4:Big East] | L | 16-43 | |
| 10/15 | H | South Florida (5-7) | [P4:Big East] | W | 16-10 | |
| 10/26 | A | Pitt (6-6) | [P4:Big East] | L | 20-35 | |
| 11/5 | H | Syracuse (5-7) | [P4:Big East] | W | 28-21 | |
| 11/19 | H | Louisville (7-5) | [P4:Big East] | L | 20-34 | |
| 11/26 | H | Rutgers (8-4) | [P4:Big East] | W | 40-22 | |
| 12/3 | A | Cincinnati (9-3) | [P4:Big East] | L | 27-35 |