ACC rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 8/29 | H | Villanova (10-2) | [FCS:CAA] | W | 27-26 | |
| 9/13 | A | C Michigan (7-5) | [G5:MAC] | W | 40-3 | |
| 9/20 | H | Maryland (7-5) | [P4:Big Ten] | L | 20-34 | |
| 9/27 | N | Notre Dame (7-5) | [P4:Ind] | L | 15-31 | |
| 10/3 | H | Louisville (9-3) | [P4:ACC] | L | 6-28 | |
| 10/11 | H | Florida St (13-0) | [P4:ACC] | L | 20-38 | |
| 10/18 | A | Wake Forest (3-9) | [P4:ACC] | W | 30-7 | |
| 10/25 | A | Clemson (9-3) | [P4:ACC] | L | 6-16 | |
| 11/1 | H | NC State (7-5) | [P4:ACC] | L | 17-24 | |
| 11/8 | H | Duke (9-3) | [P4:ACC] | L | 10-27 | |
| 11/22 | A | Pitt (6-6) | [P4:ACC] | L | 7-30 | |
| 11/29 | A | Boston College (7-5) | [P4:ACC] | L | 7-28 |