ACC rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 8/30 | N | Tennessee (8-4) | [P4:SEC] | L | 26-45 | Aflac Kickoff |
| 9/6 | H | UConn (9-3) | [G5:Ind] | W | 27-20 | |
| 9/12 | H | Colgate (5-7) | [FCS:PAT] | W | 66-24 | |
| 9/20 | A | Clemson (7-5) | [P4:ACC] | W | 34-21 | |
| 9/27 | H | Duke (8-5) | [P4:ACC] | L | 3-38 | |
| 10/4 | A | SMU (8-4) | [P4:ACC] | L | 18-31 | |
| 10/18 | H | Pitt (8-4) | [P4:ACC] | L | 13-30 | |
| 10/25 | A | Georgia Tech (9-3) | [P4:ACC] | L | 16-41 | |
| 10/31 | H | North Carolina (4-8) | [P4:ACC] | L | 10-27 | |
| 11/8 | A | Miami (10-2) | [P4:ACC] | L | 10-38 | |
| 11/22 | A | Notre Dame (10-2) | [P4:Ind] | L | 7-70 | |
| 11/29 | H | Boston College (2-10) | [P4:ACC] | L | 12-34 |