Big 12 rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/1 | H | South Dakota (4-7) | [FCS:MVFC] | W | 27-24 | |
| 9/8 | H | Mississippi St (8-4) | [P4:SEC] | L | 10-31 | |
| 9/15 | H | UTSA (3-9) | [G5:CUSA] | W | 41-17 | |
| 9/22 | A | West Virginia (8-3) | [P4:Big 12] | L | 6-35 | |
| 9/29 | H | Texas (9-4) | [P4:Big 12] | L | 14-19 | |
| 10/6 | A | Baylor (6-6) | [P4:Big 12] | L | 34-37 | |
| 10/13 | H | Oklahoma St (6-6) | [P4:Big 12] | W | 31-12 | |
| 10/27 | A | Oklahoma (12-1) | [P4:Big 12] | L | 14-51 | |
| 11/3 | A | TCU (6-6) | [P4:Big 12] | L | 13-14 | |
| 11/10 | H | Kansas (3-9) | [P4:Big 12] | W | 21-17 | |
| 11/17 | H | Texas Tech (5-7) | [P4:Big 12] | W | 21-6 | |
| 11/24 | A | Iowa State (8-4) | [P4:Big 12] | L | 38-42 |