Big 12 rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/1 | A | Auburn (8-4) | [P4:SEC] | L | 13-23 | |
| 9/8 | H | San José St (5-7) | [G5:WAC] | W | 34-14 | |
| 9/15 | H | Missouri St (6-5) | [FCS:MVFC] | W | 61-10 | |
| 9/29 | A | Texas (9-3) | [P4:Big 12] | W | 41-21 | |
| 10/6 | H | Kansas (11-1) | [P4:Big 12] | L | 24-30 | |
| 10/13 | H | Colorado (6-6) | [P4:Big 12] | W | 47-20 | |
| 10/20 | A | Oklahoma St (6-6) | [P4:Big 12] | L | 39-41 | |
| 10/27 | H | Baylor (3-9) | [P4:Big 12] | W | 51-13 | |
| 11/3 | A | Iowa State (3-9) | [P4:Big 12] | L | 20-31 | |
| 11/10 | A | Nebraska (5-7) | [P4:Big 12] | L | 31-73 | |
| 11/17 | H | Missouri (11-2) | [P4:Big 12] | L | 32-49 | |
| 11/24 | A | Fresno St (8-4) | [G5:WAC] | L | 29-45 |