Big East rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 8/31 | H | Kentucky (6-6) | [P4:SEC] | L | 2-27 | |
| 9/6 | H | Tennessee Tech (3-9) | [FCS:OVC] | W | 51-10 | |
| 9/17 | H | Kansas St (5-7) | [P4:Big 12] | W | 38-29 | |
| 9/26 | H | UConn (7-5) | [P4:Big East] | L | 21-26 | |
| 10/10 | A | Memphis (6-6) | [G5:CUSA] | W | 35-28 | |
| 10/18 | H | MTSU (5-7) | [G5:Sun Belt] | W | 42-23 | |
| 10/25 | H | South Florida (7-5) | [P4:Big East] | W | 24-20 | |
| 11/1 | A | Syracuse (3-9) | [P4:Big East] | L | 21-28 | |
| 11/8 | A | Pitt (9-3) | [P4:Big East] | L | 7-41 | |
| 11/14 | H | Cincinnati (11-2) | [P4:Big East] | L | 20-28 | |
| 11/22 | H | West Virginia (8-4) | [P4:Big East] | L | 21-35 | |
| 12/4 | A | Rutgers (7-5) | [P4:Big East] | L | 14-63 |