Big East rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/5 | H | Indiana St (1-10) | [FCS:MVFC] | W | 30-10 | |
| 9/19 | A | Kentucky (7-5) | [P4:SEC] | L | 27-31 | |
| 9/26 | A | Utah (9-3) | [G5:MWC] | L | 14-30 | |
| 10/2 | H | Pitt (9-3) | [P4:Big East] | L | 10-35 | |
| 10/10 | H | Southern Miss (7-5) | [G5:CUSA] | W | 25-23 | |
| 10/17 | A | UConn (7-5) | [P4:Big East] | L | 25-38 | |
| 10/24 | A | Cincinnati (12-0) | [P4:Big East] | L | 10-41 | |
| 10/31 | H | Arkansas St (4-8) | [G5:Sun Belt] | W | 21-13 | |
| 11/7 | A | West Virginia (9-3) | [P4:Big East] | L | 9-17 | |
| 11/14 | H | Syracuse (4-8) | [P4:Big East] | W | 10-9 | |
| 11/21 | A | South Florida (7-5) | [P4:Big East] | L | 22-34 | |
| 11/27 | H | Rutgers (8-4) | [P4:Big East] | L | 14-34 |