Big East rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 8/31 | H | Rhode Island (4-7) | [FCS:ATL10] | W | 52-7 | |
| 9/16 | H | Wake Forest (11-2) | [P4:ACC] | L | 13-24 | |
| 9/23 | A | Indiana (5-7) | [P4:Big Ten] | W | 14-7 | |
| 9/30 | H | Navy (9-3) | [G5:Ind] | L | 17-41 | |
| 10/7 | A | South Florida (8-4) | [P4:Big East] | L | 16-38 | |
| 10/14 | H | Army (3-9) | [G5:Ind] | W | 21-7 | |
| 10/20 | H | West Virginia (10-2) | [P4:Big East] | L | 11-37 | |
| 10/29 | A | Rutgers (10-2) | [P4:Big East] | L | 13-24 | |
| 11/11 | H | Pitt (6-6) | [P4:Big East] | W | 46-45 | |
| 11/18 | A | Syracuse (4-8) | [P4:Big East] | L | 14-20 | |
| 11/25 | H | Cincinnati (7-5) | [P4:Big East] | L | 23-26 | |
| 12/2 | A | Louisville (11-1) | [P4:Big East] | L | 17-48 |