Big 12 rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 8/30 | H | UAB (5-7) | [G5:CUSA] | L | 19-24 | |
| 9/6 | A | North Texas (9-3) | [G5:Sun Belt] | L | 14-52 | |
| 9/13 | H | SMU (0-12) | [G5:WAC] | W | 10-7 | |
| 9/20 | H | Sam Houston (2-9) | [FCS:LAND] | W | 27-6 | |
| 10/4 | H | Colorado (5-7) | [P4:Big 12] | W | 42-30 | |
| 10/11 | A | Texas A&M (4-8) | [P4:Big 12] | L | 10-73 | |
| 10/18 | A | Kansas (6-6) | [P4:Big 12] | L | 21-28 | |
| 10/25 | H | Texas (10-2) | [P4:Big 12] | L | 0-56 | |
| 11/1 | A | Kansas St (11-3) | [P4:Big 12] | L | 10-38 | |
| 11/8 | H | Texas Tech (7-5) | [P4:Big 12] | L | 14-62 | |
| 11/15 | A | Oklahoma (12-1) | [P4:Big 12] | L | 3-41 | |
| 11/22 | H | Oklahoma St (9-3) | [P4:Big 12] | L | 21-38 |