Big 12 rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/5 | N | Auburn (3-2) | [P4:SEC] | L | 16-17 | Aflac Kickoff |
| 9/12 | H | Prairie View (2-5) | [FCS:SWAC] | W | 44-3 | |
| 9/19 | H | Louisiana Tech (3-2) | [G5:Sun Belt] | W | 36-19 | |
| 9/26 | H | Colorado (2-3) | [P4:Big 12] | W | 23-13 | |
| 10/3 | A | Arizona St (3-2) | [P4:Big 12] | W | 55-19 | |
| 10/17 | H | TCU (2-3) | [P4:Big 12] | |||
| 10/24 | A | Kansas (2-3) | [P4:Big 12] | |||
| 10/30 | A | UCF (3-3) | [P4:Big 12] | |||
| 11/7 | H | Iowa State (3-3) | [P4:Big 12] | |||
| 11/14 | A | BYU (5-0) | [P4:Big 12] | |||
| 11/21 | H | Texas Tech (5-0) | [P4:Big 12] | |||
| 11/28 | A | Houston (5-1) | [P4:Big 12] |