Big 12 rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/12 | H | Louisiana Tech (5-4) | [G5:CUSA] | postponed | ||
| 9/19 | H | Houston (3-4) | [G5:AAC] | postponed | ||
| 9/26 | H | Kansas (0-9) | [P4:Big 12] | W | 47-14 | |
| 10/3 | A | West Virginia (5-4) | [P4:Big 12] | L | 21-27 | |
| 10/17 | H | Oklahoma St (7-3) | [P4:Big 12] | postponed | ||
| 10/24 | A | Texas (6-3) | [P4:Big 12] | L | 16-27 | |
| 10/31 | H | TCU (6-4) | [P4:Big 12] | L | 23-33 | |
| 11/7 | A | Iowa State (8-3) | [P4:Big 12] | L | 31-38 | |
| 11/14 | A | Texas Tech (4-6) | [P4:Big 12] | L | 23-24 | |
| 11/28 | H | Kansas St (4-6) | [P4:Big 12] | W | 32-31 | |
| 12/5 | A | Oklahoma (8-2) | [P4:Big 12] | L | 14-27 | |
| 12/12 | H | Oklahoma St (7-3) | [P4:Big 12] | L | 3-42 |