Big Ten rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/1 | H | Washington (10-2) | [P4:Pac-12] | L | 14-30 | |
| 9/9 | H | E Michigan (5-7) | [G5:MAC] | L | 13-16 | |
| 9/16 | H | Morgan St (1-10) | [FCS:MEAC] | W | 65-0 | |
| 9/23 | A | Nebraska (4-8) | [P4:Big Ten] | L | 17-27 | |
| 9/30 | H | Ohio State (11-2) | [P4:Big Ten] | L | 0-56 | |
| 10/14 | A | Illinois (2-10) | [P4:Big Ten] | W | 35-24 | |
| 10/21 | H | Purdue (6-6) | [P4:Big Ten] | W | 14-12 | |
| 10/28 | A | Michigan (8-4) | [P4:Big Ten] | L | 14-35 | |
| 11/4 | H | Maryland (4-8) | [P4:Big Ten] | W | 31-24 | |
| 11/11 | A | Penn State (10-2) | [P4:Big Ten] | L | 6-35 | |
| 11/18 | A | Indiana (5-7) | [P4:Big Ten] | L | 0-41 | |
| 11/25 | H | Michigan St (9-3) | [P4:Big Ten] | L | 7-40 |