Big Ten rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 8/28 | H | Ohio (8-4) | [G5:MAC] | W | 34-31 | |
| 9/6 | H | Miami OH (7-6) | [G5:MAC] | W | 45-17 | |
| 9/13 | H | Norfolk St (1-11) | [FCS:MEAC] | W | 60-10 | |
| 9/19 | H | Iowa (8-4) | [P4:Big Ten] | L | 28-38 | |
| 9/27 | A | Minnesota (7-5) | [P4:Big Ten] | L | 28-31 | |
| 10/10 | A | Washington (8-4) | [P4:Big Ten] | L | 19-38 | |
| 10/18 | H | Oregon (11-1) | [P4:Big Ten] | L | 10-56 | |
| 10/25 | A | Purdue (2-10) | [P4:Big Ten] | W | 27-24 | |
| 11/1 | A | Illinois (8-4) | [P4:Big Ten] | L | 13-35 | |
| 11/8 | H | Maryland (4-8) | [P4:Big Ten] | W | 35-20 | |
| 11/22 | A | Ohio State (12-1) | [P4:Big Ten] | L | 9-42 | |
| 11/29 | H | Penn State (6-6) | [P4:Big Ten] | L | 36-40 |