Big Ten rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/5 | H | Norfolk St (4-7) | [FCS:MEAC] | W | 63-13 | |
| 9/12 | H | Washington St (8-4) | [P4:Pac-12] | L | 34-37 | |
| 9/19 | A | Penn State (7-5) | [P4:Big Ten] | L | 3-28 | |
| 9/26 | H | Kansas (0-12) | [P4:Big 12] | W | 27-14 | |
| 10/10 | H | Michigan St (12-1) | [P4:Big Ten] | L | 24-31 | |
| 10/17 | A | Indiana (6-6) | [P4:Big Ten] | W | 55-52 | |
| 10/24 | H | Ohio State (11-1) | [P4:Big Ten] | L | 7-49 | |
| 10/31 | A | Wisconsin (9-3) | [P4:Big Ten] | L | 10-48 | |
| 11/7 | A | Michigan (9-3) | [P4:Big Ten] | L | 16-49 | |
| 11/14 | H | Nebraska (5-7) | [P4:Big Ten] | L | 14-31 | |
| 11/21 | A | Army (2-10) | [G5:Ind] | W | 31-21 | |
| 11/28 | H | Maryland (3-9) | [P4:Big Ten] | L | 41-46 |