Big Ten rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/2 | H | W Michigan (8-4) | [G5:MAC] | W | 39-20 | |
| 9/9 | A | Ball State (5-7) | [G5:MAC] | W | 24-23 | |
| 9/16 | H | S Illinois (8-3) | [FCS:MVFC] | L | 28-35 | |
| 9/23 | H | UConn (4-8) | [P4:Big East] | L | 7-14 | |
| 9/30 | H | Wisconsin (11-1) | [P4:Big Ten] | L | 17-52 | |
| 10/7 | A | Illinois (2-10) | [P4:Big Ten] | W | 34-32 | |
| 10/14 | H | Iowa (6-6) | [P4:Big Ten] | W | 31-28 | |
| 10/21 | A | Ohio State (12-0) | [P4:Big Ten] | L | 3-44 | |
| 10/28 | H | Michigan St (4-8) | [P4:Big Ten] | W | 46-21 | |
| 11/4 | A | Minnesota (6-6) | [P4:Big Ten] | L | 26-63 | |
| 11/11 | H | Michigan (11-1) | [P4:Big Ten] | L | 3-34 | |
| 11/18 | A | Purdue (8-5) | [P4:Big Ten] | L | 19-28 |