Big Ten rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/5 | H | North Texas (4-2) | [G5:AAC] | W | 52-16 | |
| 9/12 | H | Howard (2-4) | [FCS:MEAC] | W | 55-0 | |
| 9/19 | H | Western KY (3-4) | [G5:CUSA] | W | 38-0 | |
| 9/25 | H | Northwestern (4-1) | [P4:Big Ten] | W | 29-23 | |
| 10/3 | A | Rutgers (1-4) | [P4:Big Ten] | W | 47-15 | |
| 10/10 | A | Nebraska (5-1) | [P4:Big Ten] | W | 20-17 | |
| 10/17 | H | Ohio State (5-1) | [P4:Big Ten] | |||
| 10/24 | A | Michigan (3-2) | [P4:Big Ten] | |||
| 10/31 | H | Minnesota (4-2) | [P4:Big Ten] | |||
| 11/14 | H | USC (6-1) | [P4:Big Ten] | |||
| 11/21 | A | Washington (4-3) | [P4:Big Ten] | |||
| 11/28 | H | Purdue (3-4) | [P4:Big Ten] |