Big Ten rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/10 | H | Akron (7-5) | [G5:MAC] | W | 49-24 | |
| 9/17 | A | Arizona (3-8) | [P4:Pac-12] | W | 31-24 | |
| 9/24 | A | Minnesota (7-4) | [P4:Big Ten] | L | 35-42 | |
| 10/1 | H | Notre Dame (9-2) | [P4:Ind] | L | 28-49 | |
| 10/8 | H | Iowa (7-4) | [P4:Big Ten] | L | 17-34 | |
| 10/15 | H | Northwestern (7-4) | [P4:Big Ten] | L | 29-34 | |
| 10/22 | A | Wisconsin (9-3) | [P4:Big Ten] | L | 20-31 | |
| 10/29 | A | Penn State (10-1) | [P4:Big Ten] | L | 15-33 | |
| 11/5 | H | Michigan St (5-6) | [P4:Big Ten] | W | 28-21 | |
| 11/12 | H | Illinois (2-9) | [P4:Big Ten] | W | 37-3 | |
| 11/19 | A | Indiana (4-7) | [P4:Big Ten] | W | 41-14 |