Big Ten rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/4 | H | Indiana St (2-5) | [FCS:MVFC] | W | 44-19 | |
| 9/12 | H | Wake Forest (5-1) | [P4:ACC] | L | 36-38 | |
| 9/19 | A | UCLA (5-0) | [P4:Big Ten] | L | 38-52 | |
| 9/26 | H | Notre Dame (6-0) | [P4:Ind] | L | 10-49 | |
| 10/3 | A | Illinois (3-3) | [P4:Big Ten] | W | 24-17 | |
| 10/10 | H | Minnesota (4-2) | [P4:Big Ten] | W | 41-13 | |
| 10/16 | H | Washington (4-3) | [P4:Big Ten] | L | 26-38 | |
| 10/31 | A | Penn State (3-3) | [P4:Big Ten] | |||
| 11/7 | H | Maryland (2-4) | [P4:Big Ten] | |||
| 11/14 | A | Iowa (5-1) | [P4:Big Ten] | |||
| 11/21 | H | Wisconsin (4-1) | [P4:Big Ten] | |||
| 11/28 | A | Indiana (6-0) | [P4:Big Ten] |