ACC rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 8/30 | A | Boston College (7-5) | [P4:Big East] | W | 32-28 | |
| 9/6 | H | NC State (7-5) | [P4:ACC] | W | 38-24 | |
| 9/13 | H | Purdue (9-3) | [P4:Big Ten] | L | 10-16 | |
| 9/20 | H | East Carolina (1-11) | [G5:CUSA] | W | 34-16 | |
| 9/27 | A | Virginia (7-5) | [P4:ACC] | L | 24-27 | |
| 10/11 | H | Georgia Tech (6-6) | [P4:ACC] | L | 7-24 | |
| 10/18 | A | Duke (4-8) | [P4:ACC] | W | 42-13 | |
| 10/25 | A | Florida St (10-2) | [P4:ACC] | L | 24-48 | |
| 11/1 | H | Clemson (8-4) | [P4:ACC] | W | 45-17 | |
| 11/8 | A | North Carolina (2-10) | [P4:ACC] | L | 34-42 | |
| 11/15 | H | UConn (9-3) | [G5:Ind] | L | 17-51 | |
| 11/29 | H | Maryland (9-3) | [P4:ACC] | L | 28-41 |