Big 12 rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/2 | H | Colorado (4-8) | [P4:Pac-12] | L | 42-45 | |
| 9/9 | H | Nicholls (6-4) | [FCS:LAND] | W | 41-6 | |
| 9/16 | A | Houston (4-8) | [P4:Big 12] | W | 36-13 | |
| 9/23 | H | SMU (11-2) | [G5:AAC] | W | 34-17 | |
| 9/30 | H | West Virginia (8-4) | [P4:Big 12] | L | 21-24 | |
| 10/7 | A | Iowa State (7-5) | [P4:Big 12] | L | 14-27 | |
| 10/14 | H | BYU (5-7) | [P4:Big 12] | W | 44-11 | |
| 10/21 | A | Kansas St (8-4) | [P4:Big 12] | L | 3-41 | |
| 11/2 | A | Texas Tech (6-6) | [P4:Big 12] | L | 28-35 | |
| 11/11 | H | Texas (12-1) | [P4:Big 12] | L | 26-29 | |
| 11/18 | H | Baylor (3-9) | [P4:Big 12] | W | 42-17 | |
| 11/24 | A | Oklahoma (10-2) | [P4:Big 12] | L | 45-69 |