ACC rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 8/31 | H | Louisiana Tech (4-8) | [G5:CUSA] | W | 40-14 | |
| 9/7 | H | Richmond (6-6) | [FCS:CAA] | W | 23-21 | |
| 9/19 | H | Clemson (10-2) | [P4:ACC] | L | 14-26 | |
| 9/28 | H | C Michigan (6-6) | [G5:MAC] | W | 48-14 | |
| 10/5 | A | Wake Forest (4-8) | [P4:ACC] | L | 13-28 | |
| 10/12 | H | Syracuse (6-6) | [P4:ACC] | L | 10-24 | |
| 10/26 | A | Florida St (13-0) | [P4:ACC] | L | 17-49 | |
| 11/2 | H | North Carolina (6-6) | [P4:ACC] | L | 19-27 | |
| 11/9 | A | Duke (10-3) | [P4:ACC] | L | 20-38 | |
| 11/16 | A | Boston College (7-5) | [P4:ACC] | L | 21-38 | |
| 11/23 | H | East Carolina (9-3) | [G5:CUSA] | L | 28-42 | |
| 11/30 | H | Maryland (7-5) | [P4:ACC] | L | 21-41 |