Big East rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/3 | H | Notre Dame (9-2) | [P4:Ind] | L | 21-42 | |
| 9/9 | A | Ohio (4-7) | [G5:MAC] | L | 10-16 | |
| 9/17 | A | Nebraska (7-4) | [P4:Big 12] | L | 6-7 | |
| 9/24 | H | Youngstown St (8-3) | [FCS:MVFC] | W | 41-0 | |
| 9/30 | A | Rutgers (7-4) | [P4:Big East] | L | 29-37 | |
| 10/8 | H | Cincinnati (4-7) | [P4:Big East] | W | 38-20 | |
| 10/15 | H | South Florida (6-5) | [P4:Big East] | W | 31-17 | |
| 10/22 | H | Syracuse (1-10) | [P4:Big East] | W | 34-17 | |
| 11/3 | A | Louisville (9-2) | [P4:Big East] | L | 20-42 | |
| 11/12 | H | UConn (5-6) | [P4:Big East] | W | 24-0 | |
| 11/24 | A | West Virginia (10-1) | [P4:Big East] | L | 13-45 |