Big Ten rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 8/31 | H | UConn (8-4) | [G5:Ind] | W | 50-7 | |
| 9/7 | H | Michigan St (5-7) | [P4:Big Ten] | L | 24-27 | |
| 9/14 | A | Virginia (5-7) | [P4:ACC] | W | 27-13 | |
| 9/21 | H | Villanova (9-3) | [FCS:CAA] | W | 38-20 | |
| 9/28 | A | Indiana (11-1) | [P4:Big Ten] | L | 28-42 | |
| 10/11 | H | Northwestern (4-8) | [P4:Big Ten] | L | 10-37 | |
| 10/19 | H | USC (6-6) | [P4:Big Ten] | W | 29-28 | |
| 10/26 | A | Minnesota (7-5) | [P4:Big Ten] | L | 23-48 | |
| 11/9 | A | Oregon (13-0) | [P4:Big Ten] | L | 18-39 | |
| 11/16 | H | Rutgers (7-5) | [P4:Big Ten] | L | 17-31 | |
| 11/23 | H | Iowa (8-4) | [P4:Big Ten] | L | 13-29 | |
| 11/30 | A | Penn State (11-2) | [P4:Big Ten] | L | 7-44 |