Big Ten rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 8/31 | H | Miami OH (8-5) | [G5:MAC] | W | 13-6 | |
| 9/6 | H | Duke (9-3) | [P4:ACC] | L | 20-26 | |
| 9/14 | H | E Illinois (3-9) | [FCS:OVC] | W | 31-7 | |
| 9/21 | A | Washington (6-6) | [P4:Big Ten] | L | 5-24 | |
| 10/5 | H | Indiana (11-1) | [P4:Big Ten] | L | 24-41 | |
| 10/11 | A | Maryland (4-8) | [P4:Big Ten] | W | 37-10 | |
| 10/19 | H | Wisconsin (5-7) | [P4:Big Ten] | L | 3-23 | |
| 10/26 | A | Iowa (8-4) | [P4:Big Ten] | L | 14-40 | |
| 11/2 | A | Purdue (1-11) | [P4:Big Ten] | W | 26-20 | |
| 11/16 | H | Ohio State (10-2) | [P4:Big Ten] | L | 7-31 | |
| 11/23 | A | Michigan (7-5) | [P4:Big Ten] | L | 6-50 | |
| 11/30 | N | Illinois (9-3) | [P4:Big Ten] | L | 28-38 |