ACC rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 8/31 | N | Alabama (10-2) | [P4:SEC] | L | 3-42 | CHICK-fil-A KICKOFF GAME |
| 9/7 | H | NC A&T (8-3) | [FCS:MEAC] | W | 45-13 | |
| 9/14 | A | MTSU (4-8) | [G5:CUSA] | W | 41-18 | |
| 9/27 | A | Virginia Tech (8-4) | [P4:ACC] | W | 45-10 | |
| 10/5 | H | Pitt (7-5) | [P4:ACC] | L | 30-33 | |
| 10/12 | H | Georgia Tech (3-9) | [P4:ACC] | W | 41-23 | |
| 10/19 | A | Virginia (9-4) | [P4:ACC] | L | 14-48 | |
| 10/26 | A | North Carolina (6-6) | [P4:ACC] | L | 17-20 | |
| 11/9 | H | Notre Dame (10-2) | [P4:Ind] | L | 7-38 | |
| 11/16 | H | Syracuse (5-7) | [P4:ACC] | L | 6-49 | |
| 11/23 | A | Wake Forest (8-4) | [P4:ACC] | L | 27-39 | |
| 11/30 | H | Miami (6-6) | [P4:ACC] | W | 27-17 |