ACC rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/3 | A | Charlotte (5-7) | [G5:CUSA] | L | 28-31 | |
| 9/10 | H | NC A&T (5-6) | [FCS:BSOU] | W | 45-17 | |
| 9/18 | H | Northwestern (3-9) | [P4:Big Ten] | W | 30-23 | |
| 9/25 | H | Kansas (2-10) | [P4:Big 12] | W | 52-33 | |
| 10/2 | A | North Carolina (6-6) | [P4:ACC] | L | 7-38 | |
| 10/9 | H | Georgia Tech (3-9) | [P4:ACC] | L | 27-31 | |
| 10/16 | A | Virginia (6-6) | [P4:ACC] | L | 0-48 | |
| 10/30 | A | Wake Forest (10-3) | [P4:ACC] | L | 7-45 | |
| 11/6 | H | Pitt (11-2) | [P4:ACC] | L | 29-54 | |
| 11/13 | A | Virginia Tech (6-6) | [P4:ACC] | L | 17-48 | |
| 11/18 | H | Louisville (6-6) | [P4:ACC] | L | 22-62 | |
| 11/27 | H | Miami (7-5) | [P4:ACC] | L | 10-47 |