ACC rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/3 | H | Richmond (3-8) | [FCS:CAA] | L | 21-23 | |
| 9/10 | H | Stanford (11-1) | [P4:Pac-12] | L | 14-44 | |
| 9/17 | A | Boston College (4-8) | [P4:ACC] | W | 20-19 | |
| 9/24 | H | Tulane (2-11) | [G5:CUSA] | W | 48-27 | |
| 10/1 | A | FIU (8-4) | [G5:Sun Belt] | W | 31-27 | |
| 10/15 | H | Florida St (8-4) | [P4:ACC] | L | 16-41 | |
| 10/22 | H | Wake Forest (6-6) | [P4:ACC] | L | 23-24 | |
| 10/29 | H | Virginia Tech (11-2) | [P4:ACC] | L | 10-14 | |
| 11/5 | A | Miami (6-6) | [P4:ACC] | L | 14-49 | |
| 11/12 | A | Virginia (8-4) | [P4:ACC] | L | 21-31 | |
| 11/19 | H | Georgia Tech (8-4) | [P4:ACC] | L | 31-38 | |
| 11/26 | A | North Carolina (7-5) | [P4:ACC] | L | 21-37 |