Conference USA rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/1 | H | Rice (8-4) | [G5:WAC] | L | 14-21 | |
| 9/15 | A | Georgia (8-3) | [P4:SEC] | canceled | ||
| 9/22 | H | Texas (10-2) | [P4:Big 12] | L | 26-53 | |
| 9/29 | H | TCU (6-4) | [G5:CUSA] | L | 17-34 | |
| 10/6 | A | Army (3-8) | [G5:CUSA] | L | 14-28 | |
| 10/13 | H | Memphis (5-6) | [G5:CUSA] | L | 33-52 | |
| 10/20 | H | Cincinnati (7-4) | [G5:CUSA] | L | 28-29 | |
| 10/27 | A | Southern Miss (6-5) | [G5:CUSA] | L | 14-58 | |
| 11/3 | A | South Florida (8-3) | [G5:Ind] | L | 6-45 | |
| 11/10 | A | Louisville (10-2) | [G5:CUSA] | L | 10-34 | |
| 11/17 | H | UAB (6-5) | [G5:CUSA] | L | 21-43 | |
| 12/1 | A | Georgia (8-3) | [P4:SEC] | L | 7-35 |