Big 12 rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/5 | H | Oregon St (4-2) | [G5:Pac-12] | W | 33-20 | |
| 9/12 | H | Southern (3-4) | [FCS:SWAC] | W | 77-6 | |
| 9/18 | A | Texas Tech (5-0) | [P4:Big 12] | L | 26-28 | |
| 9/26 | A | GA Southern (3-4) | [G5:Sun Belt] | W | 42-28 | |
| 10/3 | H | UCF (3-3) | [P4:Big 12] | W | 27-17 | |
| 10/10 | A | Kansas St (3-2) | [P4:Big 12] | W | 35-16 | |
| 10/17 | H | Oklahoma St (4-1) | [P4:Big 12] | |||
| 10/24 | A | Utah (5-0) | [P4:Big 12] | |||
| 11/7 | H | Cincinnati (4-1) | [P4:Big 12] | |||
| 11/13 | A | Colorado (2-3) | [P4:Big 12] | |||
| 11/21 | A | West Virginia (3-3) | [P4:Big 12] | |||
| 11/28 | H | Baylor (4-1) | [P4:Big 12] |