Big Ten rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 8/30 | H | W Michigan (6-6) | [G5:MAC] | W | 28-14 | |
| 9/7 | H | South Dakota (9-2) | [FCS:MVFC] | W | 27-13 | |
| 9/14 | H | Alabama (9-3) | [P4:SEC] | L | 10-42 | |
| 9/28 | A | USC (6-6) | [P4:Big Ten] | L | 21-38 | |
| 10/5 | H | Purdue (1-11) | [P4:Big Ten] | W | 52-6 | |
| 10/12 | A | Rutgers (7-5) | [P4:Big Ten] | W | 42-7 | |
| 10/19 | A | Northwestern (4-8) | [P4:Big Ten] | W | 23-3 | |
| 10/26 | H | Penn State (11-2) | [P4:Big Ten] | L | 13-28 | |
| 11/2 | A | Iowa (8-4) | [P4:Big Ten] | L | 10-42 | |
| 11/16 | H | Oregon (13-0) | [P4:Big Ten] | L | 13-16 | |
| 11/23 | A | Nebraska (6-6) | [P4:Big Ten] | L | 25-44 | |
| 11/29 | H | Minnesota (7-5) | [P4:Big Ten] | L | 7-24 |