Big Ten rankings · National FBS rankings · All teams
| Date | H/A | Opponent | Tier:Conf | Result | Score | Notes |
|---|---|---|---|---|---|---|
| 9/5 | H | Ball State (1-5) | [G5:MAC] | W | 56-3 | |
| 9/12 | A | Texas (4-1) | [P4:SEC] | L | 23-24 | |
| 9/19 | H | Kent State (2-4) | [G5:MAC] | W | 59-3 | |
| 9/26 | H | Illinois (3-3) | [P4:Big Ten] | W | 42-19 | |
| 10/3 | A | Iowa (5-1) | [P4:Big Ten] | W | 31-14 | |
| 10/10 | H | Maryland (2-4) | [P4:Big Ten] | W | 45-16 | |
| 10/17 | A | Indiana (6-0) | [P4:Big Ten] | |||
| 10/31 | A | USC (6-1) | [P4:Big Ten] | |||
| 11/7 | H | Oregon (3-2) | [P4:Big Ten] | |||
| 11/14 | H | Northwestern (4-1) | [P4:Big Ten] | |||
| 11/21 | A | Nebraska (5-1) | [P4:Big Ten] | |||
| 11/28 | H | Michigan (3-2) | [P4:Big Ten] |